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Esophagitis can be prominent in patients with 1 poor salivary gland secretion of fluid and bicarbonate, such as in Sjogren s syndrome; 2 poor clearance of the esophagus induced by esophageal smooth muscle dysfunction, such as in scleroderma; 3 significant gastro- esophageal reflux induced by poor gastric emptying, such as seen in those with diabetes mellitus, with autonomic neuropathy, or with nonsteroidal anti- inflammatory gastropathy; or 4 increased gastric acid secretion in patients with a gastrinoma Zollinger- Ellison syndrome. doxycycline side effects long term
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Esophagitis can be prominent in patients with 1 poor salivary gland secretion of fluid and bicarbonate, such as in Sjogren s syndrome; 2 poor clearance of the esophagus induced by esophageal smooth muscle dysfunction, such as in scleroderma; 3 significant gastro- esophageal reflux induced by poor gastric emptying, such as seen in those with diabetes mellitus, with autonomic neuropathy, or with nonsteroidal anti- inflammatory gastropathy; or 4 increased gastric acid secretion in patients with a gastrinoma Zollinger- Ellison syndrome. doxycycline side effects long term
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